Can I read Circadian Urinary 6-Sulphatoxymelatonin, Cortisol Excretion and Locomotor Activity in Airline Pilots During Transmeridian Flights on EtoBox?

Circadian Urinary 6-Sulphatoxymelatonin, Cortisol Excretion and Locomotor Activity in Airline Pilots During Transmeridian Flights by Jesús A.F. Tresguerres; Carmen Ariznavarreta; Blanca Granados; Mercedes Martín; María A. Villanúa; Diego A. Golombek; Daniel P. Cardinali is a Neuroscience article available to read on EtoBox.

What is Circadian Urinary 6-Sulphatoxymelatonin, Cortisol Excretion and Locomotor Activity in Airline Pilots During Transmeridian Flights about?

Airline pilots divided into two groups of age (over and under 50 years) were studied before, during and after westbound (Madrid–Mexico City–Madrid, n=12) and eastbound (Madrid–Tokyo–Madrid, n=21) flights. A group of 10 age‐matched people staying in Madrid were submitted to the same tests and served as a control group. Changes in urinary 6‐sulphatoxymelatonin (6‐aMTs) and free cortisol excretion (determined in 6‐hr intervals) were measured by radioimmunoassay. Using wrist actigraphy, the circadian locomotor activity rhythm (LAR) was also monitored. Maximal baseline excretion of 6‐aMTs occurred between 00:00 and 12:00 hr and maximal excretion of cortisol took place between 6:00 and 12:00 hr in the control group. Analysed globally, older pilots exhibited significantly lower values of 6‐aMTs than younger ones. In both flight directions, pilots maintained the pattern of excretion of 6‐aMTs, corresponding to baseline. The return flight to Madrid from Mexico and Tokyo coincided with a maximum in 6‐aMTs excretion. Pilots kept the cortisol pattern found in the control group, with those over 50 years of age exhibiting significantly lower cortisol values than the younger ones. A 7‐hr delay in

Who reads Circadian Urinary 6-Sulphatoxymelatonin, Cortisol Excretion and Locomotor Activity in Airline Pilots During Transmeridian Flights?

Author

Jesús A.F. Tresguerres; Carmen Ariznavarreta; Blanca Granados; Mercedes Martín; María A. Villanúa; Diego A. Golombek; Daniel P. Cardinali

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0742-3098)

Published

2001

Language

EN

Field

Neuroscience (Life Sciences)