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Allele frequency distributions of six Amp-FLPS (D1S80, APO-B, VWA, TH01, CSF1PO and HPRTB) in a Mexican population by H. Rangel-Villalobos; F. Rivas; M. Torres-Rodrı́guez; A.R. Jaloma-Cruz; M.P. Gallegos-Arreola; J. López-Satow; J.M. Cantú; L.E. Figuera is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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Six amplified fragment length polymorphisms or Amp-FLPs, two VNTRs (D1S80 and APO-B) and four STRs (VWA, TH01, CSF1PO and HPRTB), were typed in a Mexican population of the Jalisco state by means of non-denaturing polyacrylamide gel electrophoresis (native PAGE) in standard gel units and silver staining. Genotype distribution was in agreement with Hardy-Weinberg expectations (HWE) for all six markers. Heterozygosity ranged from 70.6 to 83.5%, the cumulated chance of exclusion (CE) and power of discrimination (PD) were 99.4 and 99.99%, respectively. STRs and D1S80 allele frequency distributions (AFD) were similar (P > 0.05) to U.S. Hispanics, but different to U.S. Caucasians and African-Americans. APO-B exhibited similarities with White Brazilians, Spaniards, but differences (P < 0.05) with Amerindian and Black Brazilians.

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Author

H. Rangel-Villalobos; F. Rivas; M. Torres-Rodrı́guez; A.R. Jaloma-Cruz; M.P. Gallegos-Arreola; J. López-Satow; J.M. Cantú; L.E. Figuera

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0379-0738)

Published

1999

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)