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Lecture 3 by Professor Steve Hill focuses on the genetic basis of cancers, emphasizing how mutations in oncogenes and tumor suppressor genes can lead to cancer. Key concepts include gene dysregulation through splicing mutations, gene deletions, amplifications, and chromosomal rearrangements, with specific examples like RB1, INK4, and MDM2. The lecture also discusses the role of histone modifications and transcription factors in cancer development.
- Author
- ieunsoo654
- Language
- EN