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Effect of neutron-gamma radiation on dopamine and serotonin metabolism in the rat brain: A regional analysis by Olivier Foulon; Frédéric Lalouette; Fabrice Lambert; Serge Martin; Marc Fatôme; Christine Martin is a Neuroscience article available to read on EtoBox.
What is Effect of neutron-gamma radiation on dopamine and serotonin metabolism in the rat brain: A regional analysis about?
The concentrations of dopamine (DA) and its metabolites and the levels of 5-hydroxyindoleacetic acid (5-HIAA), the metabolite of serotonin, were determined in discrete cerebral areas of rats 3 hr after (neutron-gamma) irradiation at 4 and 7 Gy. After the 7 Gy irradiation, no significant effect was observed. After the 4 Gy exposure, the most marked difference between irradiated and control rats was in the levels of DA and its metabolites in the striatum. We observed a decrease of DA, HVA, and DOPAC levels in the striatum and an opposite pattern in the substantia nigra. Whatever the brain area observed, an increase of 5-HIAA levels was noted.
Who reads Effect of neutron-gamma radiation on dopamine and serotonin metabolism in the rat brain: A regional analysis?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Olivier Foulon; Frédéric Lalouette; Fabrice Lambert; Serge Martin; Marc Fatôme; Christine Martin
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0360-4012)
- Published
- 1999
- Language
- EN
- Field
- Neuroscience (Life Sciences)