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This study investigates the hepatic metabolism of polychlorinated biphenyls (PCBs) in human and rat liver microsomes, focusing on the kinetics and potential nuclear receptor affinities of various PCB congeners. The findings reveal species-specific differences in metabolism, with similar metabolite profiles observed between humans and rats, and highlight the production of di-OH-PCBs from certain congeners. Additionally, the research indicates a high affinity between PCBs and specific nuclear receptors, sugge

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w87980066

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EN