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Full-limb and Knee Radiography Assessments of Varus-valgus Alignment and Their Relationship to Osteoarthritis Disease Features by Magnetic Resonance Imaging by Sakeba N. Issa; Dorothy Dunlop; Alison Chang; Jing Song; Pottumarthi V. Prasad; Ali Guermazi; Charles Peterfy; September Cahue; Meredith Marshall; Dipali Kapoor; Karen Hayes; Leena Sharma is a Medicine article available to read on EtoBox.
What is Full-limb and Knee Radiography Assessments of Varus-valgus Alignment and Their Relationship to Osteoarthritis Disease Features by Magnetic Resonance Imaging about?
## Abstract ## Objective To examine the correlation between hip‐knee‐ankle and femur‐tibia radiograph angles, calculate the offset of the femur‐tibia angle with respect to the hip‐knee‐ankle angle, calculate the sensitivity and specificity and area under the receiver operating characteristic (ROC) curve of the femur‐tibia angle, and examine the relationship of malalignment by each approach with osteoarthritis (OA) tissue pathology in the mechanically stressed compartment using magnetic resonance imaging (MRI). ## Methods Individuals with knee OA underwent full‐limb and knee radiographs and knee MRI. Linear regression was used to determine if the 2 angles differed systematically and to identify the cutoff. Alignment means for MRI grades were compared using Dunnett's __t__‐test. ## Results In the 146 participants (109 women, mean age 70 years, body mass index 30.6 kg/m^2^), femur‐tibia and hip‐knee‐ankle angles correlated (r = 0.86; 95% confidence interval [95% CI] 0.81, 0.90). On average, the femur‐tibia angle was 3.4° more valgus (3.0° in women and 4.7° in men); after correction, its sensitivity and specificity (to predict the hip‐knee‐ankle angle) were 0.84 and 0.84 for identifyin
Who reads Full-limb and Knee Radiography Assessments of Varus-valgus Alignment and Their Relationship to Osteoarthritis Disease Features by Magnetic Resonance Imaging?
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- Author
- Sakeba N. Issa; Dorothy Dunlop; Alison Chang; Jing Song; Pottumarthi V. Prasad; Ali Guermazi; Charles Peterfy; September Cahue; Meredith Marshall; Dipali Kapoor; Karen Hayes; Leena Sharma
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0004-3591)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)