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Postimplant rectal dosimetry is not dependent on 103Pd or 125I seed activity by Gregory S. Merrick; John Sylvester; Peter Grimm; Zachariah A. Allen; Wayne M. Butler; Joshua L. Reed; Jonathan Khanjian is a Medicine article available to read on EtoBox.

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PURPOSE: In this study, the effect of prostate brachytherapy seed activity on postimplant rectal dosimetry was evaluated in Pro-Qura (Prostate Brachytherapy Quality Assurance; Seattle, WA) proctored, community-based programs. METHODS AND MATERIALS: Twenty-three hundred patients (1563 iodine-125 [ 125 I] and 737 palladium-103 [ 103 Pd]) from 78 brachytherapists with postimplant rectal dosimetry were identified. Seed activity was stratified into three tertiles for each isotope (<0.300, 0.301e0.326, and O0.326 mCi/seed for 125 I and <1.330, 1.331e1.547, and O1.547 mCi/seed for 103 Pd). Postimplant dosimetry was performed in a standardized fashion. The rectum was contoured by outlining the outer rectal wall. The volume of the rectum receiving 100% of the prescription dose (R 100 ) was calculated in cubic centimeters. The prostate V 100 and D 90 volumes were also calculated. RESULTS: The mean prostate volume was 35.8 and 32.3 cm 3 for 125 I and 103 Pd. The median time to postimplant CT was 30 days. For 125 I, the V 100 increased from 91.0% to 93.7% ( p 5 0.012) and the D 90 increased from 105.9% to 108.7% ( p!0.001) for the lowest to the highest 125 I seed activities. In contrast, no si

Who reads Postimplant rectal dosimetry is not dependent on 103Pd or 125I seed activity?

Author

Gregory S. Merrick; John Sylvester; Peter Grimm; Zachariah A. Allen; Wayne M. Butler; Joshua L. Reed; Jonathan Khanjian

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1538-4721)

Published

2011

Language

EN

Field

Medicine (Health Sciences)