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What is Unit 1.3 (Aminoglycosides) about?
Aminoglycosides are antibiotics characterized by amino sugars linked glycosidically, with a pharmacophoric 1,3-diaminoinositol moiety. They exert a bactericidal effect by binding to the 16S rRNA of the 30S ribosomal subunit, disrupting protein synthesis through mistranslation. Neomycin, derived from Streptomyces fradiae, is commonly used for bowel sanitation and treating E. coli infections.
- Author
- guptavansh748
- Language
- EN