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Relative Contributions of Various Endogenous and Exogenous Factors to the Mosquito Microbiota by Bogale, Haikel N.; Cannon, Matthew V.; Keita, Kalil; Camara, Denka; Barry, Yaya; Keita, Moussa; Coulibaly, Drissa; Kone, Abdoulaye K.; Doumbo, Ogobara K.; Thera, Mahamadou A.; Plowe, Christopher V.; Travassos, Mark; Irish, Seth; Serre, David is a Medicine article available to read on EtoBox.
What is Relative Contributions of Various Endogenous and Exogenous Factors to the Mosquito Microbiota about?
## Abstract ## Background The commensal microbiota of mosquitoes impacts their development, immunity, and competency, and could provide a target for alternative entomological control approaches. However, despite the importance of the mosquito/microbiota interactions, little is known about the relative contribution of endogenous and exogenous factors in shaping the bacterial communities of mosquitoes. ## Methods We used a high-throughput sequencing-based assay to characterize the bacterial composition and diversity of 665 individual field-caught mosquitoes, as well as their species, genotype at an insecticide resistance locus, blood-meal composition, and the eukaryotic parasites and viruses they carry. We then used these data to rigorously estimate the individual effect of each parameter on the bacterial diversity as well as the relative contribution of each parameter to the microbial composition. ## Results Overall, multivariate analyses did not reveal any significant contribution of the mosquito species, insecticide resistance, or blood meal to the bacterial composition of the mosquitoes surveyed, and infection with parasites and viruses only contributed very marginally. The main
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It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Bogale, Haikel N.; Cannon, Matthew V.; Keita, Kalil; Camara, Denka; Barry, Yaya; Keita, Moussa; Coulibaly, Drissa; Kone, Abdoulaye K.; Doumbo, Ogobara K.; Thera, Mahamadou A.; Plowe, Christopher V.; Travassos, Mark; Irish, Seth; Serre, David
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2008-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc.; Research Square (ISSN 1756-3305)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)