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Can I read Germ cell tumors of the head and neck: Report from the MAKEI Study Group on EtoBox?
Germ cell tumors of the head and neck: Report from the MAKEI Study Group by Beate Bernbeck; Dominik T. Schneider; Benedikt Bernbeck; Susanne Koch; Carmen Teske; Jürgen Lentrodt; Dieter Harms; Ulrich Göbel; Gabriele Calaminus; on Behalf of the MAKEI‐Study Group is a Medicine article available to read on EtoBox.
What is Germ cell tumors of the head and neck: Report from the MAKEI Study Group about?
## Abstract ## Background Germ cell tumors (GCTs) of the head and neck region are rare but may pose significant problems for perinatal management as well as surgical and adjuvant therapy. ## Procedure Thirty‐two prospectively reported patients from the German MAKEI studies (Maligne Keimzelltumoren) were analyzed with regard to perinatal management and long‐term survival. ## Results Twenty‐three tumors were diagnosed around birth and four during the first 3 months of life. All were primarily diagnosed as teratomas, but in two tumors, yolk sac tumor (YST) foci were identified. Another pure teratoma was diagnosed at 12 months. Four tumors were diagnosed after the first year of life and showed YST as leading histology. Most neonates presented with huge tumors causing external airway obstruction. All tumors were resected (complete resection, 16/26 patients with complete surgical information; incomplete resection, 10/26 patients). Eight tumors including five of six YSTs were treated with chemotherapy. In total, six patients relapsed. Relapse rate was higher after incomplete (5/10 patients) than after complete resection (1/16 patients). Accordingly, more relapses were observed in pharynge
Who reads Germ cell tumors of the head and neck: Report from the MAKEI Study Group?
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- Author
- Beate Bernbeck; Dominik T. Schneider; Benedikt Bernbeck; Susanne Koch; Carmen Teske; Jürgen Lentrodt; Dieter Harms; Ulrich Göbel; Gabriele Calaminus; on Behalf of the MAKEI‐Study Group
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)