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Can I read Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation: Isolated Hepatic Veno-Occlusive Disease on EtoBox?
Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation: Isolated Hepatic Veno-Occlusive Disease by Mylène Sebagh; Daniel Azoulay; Bruno Roche; Emir Hoti; Vincent Karam; Elina Teicher; Laurence Bonhomme-Faivre; Faouzi Saliba; Jean-Charles Duclos-Vallée; Didier Samuel is a Medicine article available to read on EtoBox.
What is Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation: Isolated Hepatic Veno-Occlusive Disease about?
After liver transplantation (LT), hepatic veno-occlusive disease (VOD), which is also known as sinusoidal obstruction syndrome (SOS), has been reported initially in relation to azathioprine use and subsequently in relation to acute rejection (AR). Isolated veno-occlusive disease (iVOD)/SOS raises some questions about its significance and especially its treatment. From the post-LT biopsy samples of 1364 patients (2000-2008), 31 patients with index biopsy samples showing VOD/SOS (2.3%) were identified. After a review of the index biopsy samples and previous biopsy samples, those patients not exposed to azathioprine therapy were subdivided into 2 groups according to the absence or presence of AR. Fifteen of the 31 patients had no previous evidence of AR, whereas 16 experienced episodes of AR (before or concurrently with VOD). The 2 groups were similar in terms of demographic and clinical data and the range of histological centrilobular changes. AR episodes were characterized by an endothelial predilection. iVOD/SOS occurred later than acute rejection-related veno-occlusive disease (AR-VOD)/SOS (mean times of 65 and 4.4 months, respectively, P 1⁄4 0.0098). There was a tendency for iVOD
Who reads Significance of isolated hepatic veno-occlusive disease/sinusoidal obstruction syndrome after liver transplantation: Isolated Hepatic Veno-Occlusive Disease?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Mylène Sebagh; Daniel Azoulay; Bruno Roche; Emir Hoti; Vincent Karam; Elina Teicher; Laurence Bonhomme-Faivre; Faouzi Saliba; Jean-Charles Duclos-Vallée; Didier Samuel
- Publisher
- Ovid Technologies (Wolters Kluwer Health)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)