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The article discusses the continuous flow C-glycosylation process via metal-halogen exchange for the efficient manufacturing of remdesivir, the first approved treatment for COVID-19. It highlights the challenges and optimizations in the synthesis, particularly focusing on the C-glycosylation step, which was successfully transferred to a flow setup to improve processing time and stability. The study emphasizes the potential of continuous flow technology in enhancing the production of active pharmaceutical in
- Author
- arun manchekar
- Language
- EN