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Volumetric interpolated contrast‐enhanced MRA for the diagnosis of pulmonary embolism in an ex vivo system by Jürgen Biederer; Carsten Liess; Nikolas Charalambous; Martin Heller is a Medicine article available to read on EtoBox.

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## Abstract ## Purpose To implement a three‐dimensional gradient‐recalled echo (GRE) volumetric interpolated breath‐hold examination (VIBE) sequence for pulmonary contrast‐enhanced MRA (CE‐MRA) in an experimental setup. ## Materials and Methods Eight porcine lungs were intubated, inflated inside a chest phantom, and examined at 1.5 T during slow perfusion (2–300 mL/minute). Three‐dimensional‐MRA was performed with and without contrast agent using three‐dimensional‐GRE (VIBE) with TR/TE = 4.5/1.9 msec, TA = 23 seconds, FOV = 390 mm, FA = 12°/30°, as well as a standard three‐dimensional‐GRE sequence and T2 fast spin‐echo (FSE) sequences. Four of the eight lungs were embolized with autologous blood clots. By consensus readings, two observers evaluated the detectability of peripheral vessels, signal intensity over vessels and lung, and visualization of emboli. Digital subtraction angiograms served as a control to document vessel patency. ## Results Prior to contrast administration, three‐dimensional‐VIBE/12° yielded the best results for lung parenchyma signal and visualization of small vessels (third‐order, __P__ < 0.01); however, no emboli were detected (due to lack of contrast). Afte

Who reads Volumetric interpolated contrast‐enhanced MRA for the diagnosis of pulmonary embolism in an ex vivo system?

Author

Jürgen Biederer; Carsten Liess; Nikolas Charalambous; Martin Heller

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)

Published

2004

Language

EN

Field

Medicine (Health Sciences)