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Can I read Bradykinin Induces Superoxide Anion Release from Human Endothelial Cells on EtoBox?
Bradykinin Induces Superoxide Anion Release from Human Endothelial Cells by James A. Holland; Kirkwood A. Pritchard; Miguel A. Pappolla; Michael S. Wolin; Nancy J. Rogers; Michael B. Stemerman is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Bradykinin Induces Superoxide Anion Release from Human Endothelial Cells about?
## Abstract The time‐dependent release of superoxide anion (O) from bradykinin (Bk)‐stimulated human umbilical vein endothelial cells (EC) was measured as the superoxide dismutase‐inhibitable reduction of ferricytochrome C employing a novel application of microspectrophotometry. In the absence of Bk, O release by EC was not detectable. EC exposure to Bk (10^−6^ to 10^−5^ M) resulted in a rapid release of O. The release of O occurred within 5 minutes of exposure. O release was partially inhibited by indomethacin (63 ± 6%), thus suggesting that arachidonic acid metabolism, through cyclooxygenase, contributes to EC O production. EC O release may be an important component in the pathophysiologic actions of Bk on vascular function.
Who reads Bradykinin Induces Superoxide Anion Release from Human Endothelial Cells?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- James A. Holland; Kirkwood A. Pritchard; Miguel A. Pappolla; Michael S. Wolin; Nancy J. Rogers; Michael B. Stemerman
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0021-9541)
- Published
- 1990
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)