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A conformational study of ligands for omega modulatory sites of GABAa receptors by NOESY NMR spectroscopy and distance geometry by Anne Olivier; Mireille Sevrin; François Durant; Pascal George is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is A conformational study of ligands for omega modulatory sites of GABAa receptors by NOESY NMR spectroscopy and distance geometry about?

Conlbrmational analysis by NOESY NMR spectroscopy and Distance Geometry of an co~ selective (zolpidem) and a non selective (saripidem) ligand of to modulatory sites suggests that the single set of conlbrmations observed with zolpidem could be account for its tot selective properties. The methodology applied in this study appears to be a powerful technique to explore conformational space of non-peptidic ligands of GABAA receptor subtypes.

Who reads A conformational study of ligands for omega modulatory sites of GABAa receptors by NOESY NMR spectroscopy and distance geometry?

Author

Anne Olivier; Mireille Sevrin; François Durant; Pascal George

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)

Published

1997

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)