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Adenosine and Adenosine Receptors by Michael Williams (auth.), Michael Williams (eds.) is a nonfiction available to read on EtoBox.

What is Adenosine and Adenosine Receptors about?

Historically, the major emphasis on the study of purinergic systems has been predominantly in the areas of physiology and gross pharmacology. The last decade has seen an exponential in crease in the number of publications related to the role of both adenosine and A TP in mammalian tissue function, a level of interest that has evolved from a more molecular focus on the identity of adenosine and A TP receptor subtypes and the search for selective ligands and development of radioligand binding assays by Fred Bruns and colleagues (especially that for A receptors) that played z a highly significant role in advancing research in the area. In the 60 years since adenosine was first shown to be a potent hypotensive agent, a considerable investment has been made by several pharmaceutical companies-including Abbott, Byk Gulden, Takeda, Warner-LambertlParke Davis, Boehringer Mann heim, Boehringer Ingelheim, Nelson/Whitby Research and CffiA Geigy-as well as John Daly's laboratory at the National Institutes of Health, to design new adenosine receptor ligands, and both agon ists and antagonists with the aim of developing new therapeutic entiities. Numerous research tools have derived from these e

Who reads Adenosine and Adenosine Receptors?

Author

Michael Williams (auth.), Michael Williams (eds.)

Publisher

Humana Press

Published

1990

Language

EN

ISBN

9781461245049

Category

nonfiction

Subjects

Science, Medical, Stem