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Proteome-wide identification of non-histone lysine methylationin tomato during fruit ripeningYour article is being processed as a regular item to be included in a regular issue. Please confirm if this is correct or if your article should 1 Introduction 2 Materials and methods 2 Sample collection and protein extraction 2 Trypsin digestion and HPLC fractionation 2 Affinity enrichment of lysine-methylated peptides 2 LC-MS/MS analysis 4 Database search and motif analysis 4 Bioinformatics analysis 5 Site-directed mutagenesis, purification of recombinant proteins and activity analysis 5 Real-time quantitative PCR (RT-qPCR) analysis 5 Statistical analysis 5 Results and discussion 5 Proteome-wide analysis of lysine methylation sites and proteins in tomato 5 Motif characteristics of methylated peptides in tomato 5 Functional annotation of methylated proteins in tomato 5 Methylated proteins related to important biological processes 7 Effects of the methylation modification on protein activity 10 Expression profiles of many genes encoding proteins subjected to methylation during fruit ripening 10 Conclusion 11 CRediT authorship contribution statement 11 Declaration of Competing Interest 11 A

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