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What is Belinostat: Efficacy and Development Insights about?

Belinostat is a pan HDAC inhibitor showing multi-targeted effects, including reactivation of tumor suppressor genes and increased DNA repair mechanisms. Clinical trials reveal its efficacy in treating T-cell lymphomas, with a 26% overall response rate in relapsed/refractory patients, and it is well tolerated with manageable side effects. Ongoing studies are exploring its combination with other therapies to enhance treatment outcomes for various malignancies.

Author

Farma Corina

Language

EN