Can I read High seroprevalence of anti-SARS-CoV-2 antibodies among Ethiopian healthcare workers on EtoBox?

High seroprevalence of anti-SARS-CoV-2 antibodies among Ethiopian healthcare workers by Tesfaye Gelanew; Berhanu Seyoum; Andargachew Mulu; Adane Mihret; Markos Abebe; Liya Wassie; Baye Gelaw; Abebe Sorsa; Yared Merid; Yilkal Muchie; Zelalem Teklemariam; Bezalem Tesfaye; Mahlet Osman; Gutema Jebessa; Abay Atinafu; Tsegaye Hailu; Antenehe Habte; Dagaga Kenea; Anteneh Gadisa; Desalegn Admasu; Emnet Tesfaye; Timothy A. Bates; Jote Tafese Bulcha; Rea Tschopp; Dareskedar Tsehay; Kim Mullholand; Rawleigh Howe; Abebe Genetu; Fikadu G. Tafesse; Alemseged Abdissa is a Medicine article available to read on EtoBox.

What is High seroprevalence of anti-SARS-CoV-2 antibodies among Ethiopian healthcare workers about?

## Abstract ## Background COVID-19 pandemic has a devastating impact on the economies and health care system of sub-Saharan Africa. Healthcare workers (HWs), the main actors of the health system, are at higher risk because of their occupation. Serology-based estimates of SARS-CoV-2 infection among HWs represent a measure of HWs’ exposure to the virus and could be used as a guide to the prevalence of SARS-CoV-2 in the community and valuable in combating COVID-19. This information is currently lacking in Ethiopia and other African countries. This study aimed to develop an in-house antibody testing assay, assess the prevalence of SARS-CoV-2 antibodies among Ethiopian high-risk frontline HWs. ## Methods We developed and validated an in-house Enzyme-Linked Immunosorbent Assay (ELISA) for specific detection of anti-SARS-CoV-2 receptor binding domain immunoglobin G (IgG) antibodies. We then used this assay to assess the seroprevalence among HWs in five public hospitals located in different geographic regions of Ethiopia. From consenting HWs, blood samples were collected between December 2020 and February 2021, the period between the two peaks of COVID-19 in Ethiopia. Socio-demographic and

Who reads High seroprevalence of anti-SARS-CoV-2 antibodies among Ethiopian healthcare workers?

Author

Tesfaye Gelanew; Berhanu Seyoum; Andargachew Mulu; Adane Mihret; Markos Abebe; Liya Wassie; Baye Gelaw; Abebe Sorsa; Yared Merid; Yilkal Muchie; Zelalem Teklemariam; Bezalem Tesfaye; Mahlet Osman; Gutema Jebessa; Abay Atinafu; Tsegaye Hailu; Antenehe Habte; Dagaga Kenea; Anteneh Gadisa; Desalegn Admasu; Emnet Tesfaye; Timothy A. Bates; Jote Tafese Bulcha; Rea Tschopp; Dareskedar Tsehay; Kim Mullholand; Rawleigh Howe; Abebe Genetu; Fikadu G. Tafesse; Alemseged Abdissa

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)