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Appearances of Conventional and Contrast-Enhanced Transrectal Ultrasonography of Granulomatous Prostatitis by Y. Li; J. Tang; A. Guo is a Medicine article available to read on EtoBox.

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Purpose: This study is aimed to investigate the clinical usefulness of the novel ultrasound contrast agent Sonazoid in the diagnosis of prostatic cancer. Material & Methods: A preliminary study was carried out in December 2009 under the approval of IRB in our Hospital, and we started this prospective clinical trial from January, 2010. We here report the early results in 246 consecutive cases treated between January and August, 2010. Before prostate biopsy two urologists, J.A. and K.S. examined digital rectal examination (DRE), B-mode ultrasonography (BU), power Doppler ultrasound (PDU), and checked lesions of suspected cancer. After intravenous infusion of Sonazoid, targeted biopsies in the suspected lesions by each modalities including Sonazoid-enhanced ultrasonography (SEU) and the systematic biopsy on 14 sites were done. Sensitivity, specificity, PPV, NPV, and accuracy were compared between DRE, BU, PDU, and SEU. Results: The average age of the subjects was 69 years (39-87) and the median PSA was 7.5 ng/ml ( .4 -3606.2). Of 246 cases 150 were prostate cancer (61.0%). The sensitivity, specificity, PPV, NPV, and accuracy were 62.0%, 55.2%, 68.4%, 48.2%, and 59.3% by DRE, 70.0%, 43

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Author

Y. Li; J. Tang; A. Guo

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0301-5629)

Published

2011

Language

EN

Field

Medicine (Health Sciences)