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Oxytocin‐release‐deficit and Social Cognition in Craniopharyngioma Patients by Brandi, MarieâLuise; Gebert, Dorothea; Kopczak, Anna; Auer, Matthias K; Schilbach, Leonhard is a Neuroscience article available to read on EtoBox.

What is Oxytocin‐release‐deficit and Social Cognition in Craniopharyngioma Patients about?

Oxytocin is a neuropeptide known to affect social behaviour and cognition. Craniopharyngioma patients are considered to have an oxytocin-release-deficit caused by a rare tumour affecting the pituitary and/or the hypothalamus relevant for oxytocin production and release. To assess social behaviour and socio-cognitive abilities in this patient group, we tested 13 patients and 23 healthy controls on self-report questionnaires and an eye-tracking paradigm including fast facial emotion recognition. Additionally, saliva oxytocin levels acquired before and after a physical stress induction were available from a previous study, representing the reactivity of the oxytocin system. The data revealed three major results. First, patients with an oxytocin-release-deficit scored higher on self-reported autistic traits and reduced levels of hedonia for social encounters, although they showed no impairments in attributing mental states. Second, patients showed more difficulties in the fast emotion recognition task. Third, although automatic gaze behaviour during emotion recognition did not differ between groups, gaze behaviour was related to the reactivity of the oxytocin system across all particip

Who reads Oxytocin‐release‐deficit and Social Cognition in Craniopharyngioma Patients?

Author

Brandi, MarieâLuise; Gebert, Dorothea; Kopczak, Anna; Auer, Matthias K; Schilbach, Leonhard

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0953-8194)

Published

2020

Language

EN

Field

Neuroscience (Life Sciences)