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Retrograde Double‐labeling Study of Common Afferent Projections to the Dorsal Raphe and the Nuclear Core of the Locus Coeruleus in the Rat by Hyun S. Lee; Myung‐A Kim; Barry D. Waterhouse is a Neuroscience article available to read on EtoBox.

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## Abstract Common afferent projections to the dorsal raphe (DR) and locus coeruleus (LC) nuclei were analyzed in the rat by making paired injections of retrograde tracers, gold‐conjugated and inactivated wheatgerm agglutinin‐horseradish peroxidase (WGA‐apo‐HRP‐gold) and Fluorogold (FG), into the DR and the nuclear core of the LC. Our results demonstrate that the largest number of double‐labeled neurons was located at various preoptic regions including medial preoptic area, lateral preoptic nucleus, and ventrolateral preoptic nucleus. The majority of labeled cells were also observed at the lateral hypothalamus, where the number of labeled cells was comparable to that of neurons at the medial preoptic area or lateral preoptic nucleus. A few double‐labeled cells were observed at various hypothalamic regions including anterior, medial tuberal, posterior, and arcuate nuclei, as well as mesencephalic areas including substantia nigra compacta and ventrolateral/lateral periaqueductal gray matter. Cells were also observed at prelimbic/infralimbic prefrontal cortices, diagonal band of Broca, bed nucleus of stria terminalis, and pontine/medullary regions including various raphe nuclei, Barri

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Author

Hyun S. Lee; Myung‐A Kim; Barry D. Waterhouse

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0021-9967)

Published

2004

Language

EN

Field

Neuroscience (Life Sciences)