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Can I read SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic on EtoBox?
SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic by Neerujah Balachandren; Melanie C Davies; Jennifer A Hall; Judith M Stephenson; Anna L David; Geraldine Barrett; Helen C O’Neill; George B Ploubidis; Ephia Yasmin; Dimitrios Mavrelos is a Medicine article available to read on EtoBox.
What is SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic about?
## Abstract ## STUDY QUESTION Does maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the first trimester affect the risk of miscarriage before 13 week’s gestation? ## SUMMARY ANSWER Pregnant women with self-reported diagnosis of SARS-CoV-2 in the first trimester had a higher risk of early miscarriage. ## WHAT IS KNOWN ALREADY Viral infections during pregnancy have a broad spectrum of placental and neonatal pathology. Data on the effects of the SARS-CoV-2 infection in pregnancy are still emerging. Two systematic reviews and meta-analyses reported an increased risk of preterm birth, caesarean delivery, maternal morbidity and stillbirth. Data on the impact of first trimester infection on early pregnancy outcomes are scarce. This is the first study, to our knowledge, to investigate the rates of early pregnancy loss during the SARS-CoV-2 outbreak among women with self-reported infection. ## STUDY DESIGN, SIZE, DURATION This was a nationwide prospective cohort study of pregnant women in the community recruited using social media between 21 May and 31 December 2020. We recruited 3545 women who conceived during the SARS-CoV-2 pandemic who were <13 week
Who reads SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Neerujah Balachandren; Melanie C Davies; Jennifer A Hall; Judith M Stephenson; Anna L David; Geraldine Barrett; Helen C O’Neill; George B Ploubidis; Ephia Yasmin; Dimitrios Mavrelos
- Publisher
- Oxford University Press
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)