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Combination of Topological Parameters and Bone Volume Fraction Better Predicts the Mechanical Properties of Trabecular Bone by Laurent Pothuaud; Bert Van Rietbergen; Lis Mosekilde; Olivier Beuf; Pierre Levitz; Claude L. Benhamou; Sharmila Majumdar is a Medicine article available to read on EtoBox.
What is Combination of Topological Parameters and Bone Volume Fraction Better Predicts the Mechanical Properties of Trabecular Bone about?
Trabecular bone structure may complement bone volume/total volume fraction (BV/TV) in the prediction of the mechanical properties. Nonetheless, the direct in vivo use of information pertaining to trabecular bone structure necessitates some predictive analytical model linking structure measures to mechanical properties. In this context, the purpose of this study was to combine BV/TV and topological parameters so as to better estimate the mechanical properties of trabecular bone. Thirteen trabecular bone mid-sagittal sections were imaged by magnetic resonance (MR) imaging at the resolution of 117 x 117x 300 microm(3). Topological parameters were evaluated in applying the 3D-line skeleton graph analysis (LSGA) technique to the binary MR images. The same images were used to estimate the elastic moduli by finite element analysis (FEA). In addition to the mid-sagittal section, two cylindrical samples were cored from each vertebra along vertical and horizontal directions. Monotonic compression tests were applied to these samples to measure both vertical and horizontal ultimate stresses. BV/TV was found as a strong predictor of the mechanical properties, accounting for 89-94% of the variab
Who reads Combination of Topological Parameters and Bone Volume Fraction Better Predicts the Mechanical Properties of Trabecular Bone?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Laurent Pothuaud; Bert Van Rietbergen; Lis Mosekilde; Olivier Beuf; Pierre Levitz; Claude L. Benhamou; Sharmila Majumdar
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0021-9290)
- Published
- 2002
- Language
- EN
- Field
- Medicine (Health Sciences)