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Appearance of microvascular obstruction on high resolution first-pass perfusion, early and late gadolinium enhancement CMR in patients with acute myocardial infarction by Adam N Mather; Timothy Lockie; Eike Nagel; Michael Marber; Divaka Perera; Simon Redwood; Aleksandra Radjenovic; Ansuman Saha; John P Greenwood; Sven Plein is a Medicine article available to read on EtoBox.

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## Abstract ## Background The presence and extent of microvascular obstruction (MO) after acute myocardial infarction can be measured by first-pass gadolinium-enhanced perfusion cardiovascular magnetic resonance (CMR) or after gadolinium injection with early or late enhancement (EGE/LGE) imaging. The volume of MO measured by these three methods may differ because contrast agent diffusion into the MO reduces its apparent extent over time. Theoretically, first-pass perfusion CMR should be the most accurate method to measure MO, but this technique has been limited by lower spatial resolution than EGE and LGE as well as incomplete cardiac coverage. These limitations of perfusion CMR can be overcome using spatio-temporal undersampling methods. The purpose of this study was to compare the extent of MO by high resolution first-pass __k-t__ SENSE accelerated perfusion, EGE and LGE. ## Methods 34 patients with acute ST elevation myocardial infarction, treated successfully with primary percutaneous coronary intervention (PPCI), underwent CMR within 72 hours of admission. __k-t__ SENSE accelerated first-pass perfusion MR (7 fold acceleration, spatial resolution 1.5 mm × 1.5 mm × 10 mm, 8 slic

Who reads Appearance of microvascular obstruction on high resolution first-pass perfusion, early and late gadolinium enhancement CMR in patients with acute myocardial infarction?

Author

Adam N Mather; Timothy Lockie; Eike Nagel; Michael Marber; Divaka Perera; Simon Redwood; Aleksandra Radjenovic; Ansuman Saha; John P Greenwood; Sven Plein

Publisher

BioMed Central; Springer (Biomed Central Ltd.); New York NY: Marcel Dekker; New York N.Y.: Informa Healthcare; London: 2008-; Informa UK Limited; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1097-6647)

Published

2009

Language

EN

Field

Medicine (Health Sciences)