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Sleep architecture in patients with Juvenile Myoclonic Epilepsy by Jaidaa F. Mekky; Sonia M. Elbhrawy; Mohamed F. Boraey; Horeya M. Omar is a Medicine article available to read on EtoBox.

What is Sleep architecture in patients with Juvenile Myoclonic Epilepsy about?

## Aim: The aim is to analyze the sleep architecture using polysomnography (psg) in patients with juvenile myoclonic epilepsy (jme): (newly diagnosed and those on valproate drug) attending epilepsy clinic at alexandria university hospitals. ## Methods: This study involved 20 patients with jme on valproate (age: 22.40 ± 5.80 years; m:f = 6:14), 20 newly diagnosed patients (age: 18.55 ± 6.0 years; m:f = 6:14), and 20 matched healthy controls (age: 22.10 ± 5.0 years; m:f = 6:14). clinical assessment, electroencephalogram (eeg), evaluation with comprehensive sleep questionnaire, and psg were done for all patients. ## Results: Psg showed significant alterations in sleep architecture in the total jme group in the form of reduced mean sleep efficiency (p = 0.001), increased mean rapid eye movement (rem) onset latency (p = 0.046), decrease mean rem percentage (p = 0.011), increased mean wakefulness after sleep onset (p = 0.018), increase the index of total arousal (p = 0.005), increased mean periodic limb movement index (p = 0.001), and reduced apnea hypopnea index (p = <0.001) in comparison to control group. valproate treated group showed increased sleep efficiency (p = 0.040), decreased

Who reads Sleep architecture in patients with Juvenile Myoclonic Epilepsy?

Author

Jaidaa F. Mekky; Sonia M. Elbhrawy; Mohamed F. Boraey; Horeya M. Omar

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Medicine (Health Sciences)