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Animal Models for Muscular Dystrophy Research by Mihail Butură is a document available to read on EtoBox.
What is Animal Models for Muscular Dystrophy Research about?
The document describes animal models for muscular dystrophy (MD). It discusses how MD is a group of inherited disorders causing progressive muscle weakness. The main patterns of inheritance are X-linked recessive, autosomal dominant, and autosomal recessive. Well-known underlying genetic defects include mutations in the dystrophin gene. The mdx mouse is the best characterized model of MD, lacking dystrophin and mimicking Duchenne muscular dystrophy. However, the mdx mouse has limitations and newer models be
- Author
- Mihail Butură
- Language
- EN