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The article identifies a calcium channel subunit called a2d1 as a new biomarker for cancer stem cells in hepatocellular carcinoma. Blocking a2d1 in combination with doxorubicin treatment was shown to hinder tumor formation. The a2d1 biomarker allows for isolation of cancer stem cells, which were shown to be more tumorigenic and have stem cell-like properties compared to a2d1- cells.

Author

Malik Ibrahim

Language

EN