Can I read 3-(2-Hydroxyphenyl)imidazo[5, 1-a]isoquinoline as Cu(II) sensor, its Cu(II) complex for selective detection of CN− ion and biological compatibility on EtoBox?

3-(2-Hydroxyphenyl)imidazo[5, 1-a]isoquinoline as Cu(II) sensor, its Cu(II) complex for selective detection of CN− ion and biological compatibility by Satyajit Mahata; Souradeep Dey; Biman B. Mandal; Vadivelu Manivannan is a Materials Science article available to read on EtoBox.

What is 3-(2-Hydroxyphenyl)imidazo[5, 1-a]isoquinoline as Cu(II) sensor, its Cu(II) complex for selective detection of CN− ion and biological compatibility about?

The heterocyclic probe 3-(2-hydroxyphenyl)imidazo[5, 1-a]isoquinoline (LH) has exhibited specific recognition of Cu 2+ ion by forming a complex of formula [Cu(L) 2 ], which in turn showed recognition for CN -ions in CH 3 CN/ aqueous HEPES-buffer solution (5 mM, pH = 7.4, 6:4, v/v). The selective colorimetric and fluorescence response of LH towards Cu 2+ was achieved over other competing metal ions. Change of color from colorless to yellowish green upon incremental addition of Cu 2+ into LH solution can be easily observed with naked-eye. Emission intensity of LH was quenched in presence of Cu 2+ ion due to chelation enhanced quenching (CHEQ) process. From Job's plot and mass spectral analysis the binding stoichiometry was found to 2:1 between LH and Cu 2+ . Binding of the probe LH with Cu 2+ ion can be reversed by sequestering Cu 2+ ion using Na 2 EDTA solutions. Red shift in UV-visible spectrum upon addition of Cu 2+ ion into LH solution was a consequence of decrease in HOMO-LUMO energy gap. From life time decay curve the average fluorescence life time (τ) was found to be 3.8 ns for free LH whereas in presence of Cu 2+ τ decreased to 2.4 ns. In addition, so formed [Cu(L) 2 ] comple

Who reads 3-(2-Hydroxyphenyl)imidazo[5, 1-a]isoquinoline as Cu(II) sensor, its Cu(II) complex for selective detection of CN− ion and biological compatibility?

Author

Satyajit Mahata; Souradeep Dey; Biman B. Mandal; Vadivelu Manivannan

Publisher

Elsevier BV

Published

2022

Language

EN

Field

Materials Science (Physical Sciences)