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High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation by Lise Piquilloud; Pierre-Yves Olivier; Jean-Christophe Richard; Valérie Thepot-Seegers; Laurent Brochard; Alain Mercat; François Beloncle is a Medicine article available to read on EtoBox.
What is High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation about?
## Background and study purpose: High flow nasal cannula (hfnc) may improve co elimination by washing out co from the upper airways. this study aimed at assessing the effect of hfnc on minute ventilation and ventilatory ratio (vr), a surrogate of dead space, in patients hospitalized for acute hypercapnic copd exacerbation. ## Methods: Physiological study comparing hfnc at 40 l/min to low flow oxygen. variations of tidal volume (vt) and minute ventilation between the two treatments were estimated from chest plethysmography. respiratory rate (rr) and arterial blood gases were measured. variations in vr were calculated. data were compared using wilcoxon tests. ## Results: Recordings performed in 10 patients. minute ventilation was reduced with hfnc by -16.2 [-30.9-0.4] % (p = 0.049). vt was not different but rr was lower during hfnc. paco was lower with hfnc compared to standard oxygen: 48.7 [46.4-58.1] vs 50.7 [48.4-57.5] mmhg (p = 0.020). vr decreased by -18.0 [-34.7 - -4.0] % (p = 0.020) with hfnc. ## Conclusions: In patients recovering from acute copd exacerbation, the use of hfnc reduced rr, minute ventilation, paco and vr compared to standard oxygen. these changes are consistent
Who reads High flow nasal cannula improves breathing efficiency and ventilatory ratio in COPD patients recovering from an exacerbation?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Lise Piquilloud; Pierre-Yves Olivier; Jean-Christophe Richard; Valérie Thepot-Seegers; Laurent Brochard; Alain Mercat; François Beloncle
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)