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This study presents a validated UPLC–MS/MS method for quantifying maackiain and its metabolites, maackiain-sulfate and maackiain-glucuronide, in blood. The method demonstrated high sensitivity with a lower limit of detection of 4.88 nM and was successfully applied in pharmacokinetic studies in mice and cell culture models. The results indicate the method

Author

Vũ Hương

Language

EN