Can I read Salivary IgA subclasses and bacteria‐reactive IgA in patients with aggressive periodontitis on EtoBox?

Salivary IgA subclasses and bacteria‐reactive IgA in patients with aggressive periodontitis by S. Hägewald; J.‐P. Bernimoulin; E. Köttgen; A. Kage is a Dentistry article available to read on EtoBox.

What is Salivary IgA subclasses and bacteria‐reactive IgA in patients with aggressive periodontitis about?

The local salivary immunoglobulin A (IgA) response in patients with aggressive periodontitis to oral microorganisms and its role for the pathogenesis has not been determined. This study investigated the hypothesis that aggressive periodontitis patients have impaired oral secretory immunity. Our test group was made‐up of 19 aggressive periodontitis patients and 19 age‐ and gender‐matched periodontally healthy controls. Total IgA, IgA subclass 1, IgA subclass 2 and IgA reactive to __Actinobacillus actinomycetemcomitans__ Y4, __Treponema denticola__ ATCC 35404 and __Candida albicans__ DSM 3454 were determined by enzyme‐linked immunosorbent assay in whole unstimulated and stimulated saliva. A statistically significantly lower concentration and secretion rate of total salivary IgA (__P__ < 0.01) and IgA1 (__P__ < 0.001) was found in the aggressive periodontitis group in resting and stimulated saliva. A decrease of IgA2 (__P__ < 0.05) was seen in resting saliva. Although only minor differences were detected in the concentration and secretion of bacteria‐reactive IgA in both groups, the proportion of bacteria‐reactive IgA from the total IgA was significantly higher (__P__ < 0.01) in the a

Who reads Salivary IgA subclasses and bacteria‐reactive IgA in patients with aggressive periodontitis?

Author

S. Hägewald; J.‐P. Bernimoulin; E. Köttgen; A. Kage

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0022-3484)

Published

2002

Language

EN

Field

Dentistry (Health Sciences)