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METHODS IN ENZYMOLOGY VOLUME 241 RETROVIRAL PROTEASES by Lawrence C. Kuo, Jules A. Shafer (Eds.) is a nonfiction available to read on EtoBox.

What is METHODS IN ENZYMOLOGY VOLUME 241 RETROVIRAL PROTEASES about?

<p><P>Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.</p> <h3>Mark T. McNally</h3> <p>This volume contains a detailed treatment of retroviral proteinase expression, purification, characterization, and inhibitor design. Much of the material pertains to HIV, the causative agent of AIDS, which is justified in view of the need for antivirals to combat the AIDS epidemic. The purpose is to summarize current understanding of retroviral proteinase structure and function and present pertinent methodology for the study of these important enzymes. About a third of the book is devoted to proteinase inhibitor design because this viral protein is an attractive target for therapeutic intervention. The high level of specificity and detail make this a useful book for practitioners of retrovirology and proteinase enzymology. The multiple authors are drawn roughly equally from academic and industrial laboratories and are leaders in retroviral proteinase research. Especially useful are the many high quality illustrations. Several color and 3-dimensional figures derived from x-ray crystallography reconstructions

Who reads METHODS IN ENZYMOLOGY VOLUME 241 RETROVIRAL PROTEASES?

Author

Lawrence C. Kuo, Jules A. Shafer (Eds.)

Publisher

Academic Press, Incorporated

Published

1994

Language

EN

ISBN

9780121821425

Category

nonfiction

Subjects

Medical, Science, Technology

Updated

2026-03-24