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Synthesis and Anthelmintic Activity of Isopelletierine and a Series of Side-chain Homologues by J. van Noordwijk; J. J. Mellink; B. J. Visser; J. H. Wisse is a Chemistry article available to read on EtoBox.
What is Synthesis and Anthelmintic Activity of Isopelletierine and a Series of Side-chain Homologues about?
## Abstract The preparation and anthelmintic properties of isopelletierine and four side‐chain homologues are described. The compounds were prepared from Δ~1~‐piperideine and 3‐oxo‐acids at pH 4‐5. pK′~a−~ and Rf‐values were determined. Anthelmintic activity as tested __in vitro__ on the liver fluke, by three methods, was highest for 1‐(2′‐piperidyl)butanone‐2. The differences in anthelmintic properties of the compounds are discussed.
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It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- J. van Noordwijk; J. J. Mellink; B. J. Visser; J. H. Wisse
- Publisher
- Elsevier Science; Wiley (John Wiley & Sons); Royal Netherlands Chemical Society; Wiley (ISSN 0165-0513)
- Published
- 2010
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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