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## Context: Meatal stenosis (ms) as a potential complication of male circumcision and controversy regarding the magnitude of risk. ## Objectives: To conduct a systematic review and meta-analyses to assess (1) ms diagnosis after circumcision, (2) the potential association of ms with circumcision, and (3) a potential method of prevention. ## Data sources: Pubmed, google scholar, cochrane library and bibliographies of original studies were searched using the keywords circumcision and stenosis or stricture. ## Study selection: Studies containing original data on ms following circumcision at any age. ## Data extraction: Two reviewers independently verified study design and extracted data. ## Results: Thirty eligible studies were retrieved. a random effects meta-analysis of 27 studies (350 ms cases amongst 1,498,536 males) found that the risk of ms in circumcised males was 0.656% (95% confidence interval 0.435-0.911). meta-analysis of 3 observational studies that compared ms prevalence in circumcised and uncircumcised males found non-significantly higher prevalence in circumcised males (odds ratio 3.20; 95% confidence interval 0.73-13.9). meta-analysis of 3 randomized controlled trials i

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Author

Brian J. Morris; John N. Krieger

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Medicine (Health Sciences)