Can I read The Presence of Herpesvirus Saimiri Genomes in Virus-transformed Cells on EtoBox?

The Presence of Herpesvirus Saimiri Genomes in Virus-transformed Cells by Bernhard Fleckenstein; Ingrid Müller; Jürgen Werner is a Medicine article available to read on EtoBox.

What is The Presence of Herpesvirus Saimiri Genomes in Virus-transformed Cells about?

## Abstract __Herpesvirus saimiri (H. saimiri)__ ‐transformed cells contain both types of viral DNA, unique L‐DNA and highly repetitive H‐DNA. DNA from spleen and lymph‐node autopsies of two tumor‐bearing marmoset monkeys contained 0.14–0.75 / viral L‐DNA and 0.115–1.08 / H‐DNA. This amount of H‐DNA would be equivalent to the presence of 14–130 M‐genomes per diploid tumor tissue cell. Six virus‐transformed lymphoid cell lines, two of them virus‐producing, contained 0.69–2.27 / H‐DNA and more than 0.72–1.95 / L‐DNA. These concentrations of H‐DNA sequences correspond to 83–274 M‐genome copies per lymphoid tissue culture cell. The majority of viral genomes in transformed non‐producer lymphoid cell lines appeared to be defective, since part of the L‐sequences present in virions were found to be deleted in the genome copies of transformed cells. There was a relative excess of repetitive H‐sequences in all transformed cells in regard to the ratio of H‐DNA/L‐DNA in M‐genomes of __H. saimiri__ virions.

Who reads The Presence of Herpesvirus Saimiri Genomes in Virus-transformed Cells?

Author

Bernhard Fleckenstein; Ingrid Müller; Jürgen Werner

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

1977

Language

EN

Field

Medicine (Health Sciences)