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This document summarizes research on the 9E3/CEF4 cytokine protein in chickens. Key findings include: 1) The 9E3 protein is synthesized and secreted extremely rapidly, within 10 minutes or less. 2) It is secreted from cells as a 9 kDa protein but is processed extracellularly by the enzyme plasmin to a smaller 6-7 kDa form. 3) The smaller processed form binds to extracellular matrix molecules like collagen and laminin, but not collagen IV or fibronectin. 4) The rapid secretion and processing of 9E3 su

Author
Rambo
Language
EN

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