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Bullous Malignant Melanoma: An Unusual Differential Diagnosis of a Hemorrhagic Friction Blister by Thomas Vogt; Stephanie Brunnberg; Ulrich Hohenleutner; Michael Landthaler is a Medicine article available to read on EtoBox.
What is Bullous Malignant Melanoma: An Unusual Differential Diagnosis of a Hemorrhagic Friction Blister about?
## Background: A 66-year-old woman presented to our outpatient clinic with a 3 x 2.5-cm tense, hemorrhagic-appearing bulla on her forefoot. histopathology and immunohistochemistry confirmed a transtumoral-transepidermal blister formation within an advanced acrolentiginous malignant melanoma (mm). ## Objective: To study bullous malignant melanoma. ## Methods: Blistering in mms represents a rare but clinically important pitfall in clinical differential diagnosis. the blisters are typically due to the disruption of the cohesion between neoplastic cells and keratinocytes, but physical friction may also contribute. ## Results: Hemorrhagic blistering is, in many cases, a relatively insignificant finding in which frictional forces are imposed. ## Conclusion: The case reported here underscores that in rare cases mms, particularly if acrally located, can be complicated by hemorrhagic blistering. because of the life-threatening consequences, one should be aware of this rare differential diagnosis.
Who reads Bullous Malignant Melanoma: An Unusual Differential Diagnosis of a Hemorrhagic Friction Blister?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Thomas Vogt; Stephanie Brunnberg; Ulrich Hohenleutner; Michael Landthaler
- Publisher
- John Wiley and Sons; Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins; Wolters Kluwer Health; Ovid Technologies (Wolters Kluwer Health); Elsevier BV (ISSN 1076-0512)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)