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Risk of Haemorrhagic Stroke in Patients with Oral Anticoagulation Compared with the General Population by A. Själander; G. Engström; E. Berntorp; P. Svensson is a Medicine article available to read on EtoBox.

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**Abstract.** Själander A, Engström G, Berntorp E, Svensson P (Malmö University Hospital, University of Lund, Sweden). Risk of haemorrhagic stroke in patients with oral anticoagulation compared with the general population. __J Intern Med__ 2003; **254:** 434–438. **Objectives.** To compare the incidence of haemorrhagic stroke (HS), and the risk of fatal outcome after HS in patients with oral anticoagulation (OA) treatment and in the general population. **Design.** Five‐year cohort study. **Setting.** The Anticoagulation Clinic, Malmö University Hospital, Lund, Sweden. **Subjects.** A total of 4434 patients treated with OA (6693 treatment years) from 1 Oct 1993 to 30 Sept 1998. The population‐based Stroke Register of Malmö, Lund, Sweden (STROMA). **Results.** Forty‐eight patients had HS according to ICD 9 code 430 and 431. HS occurred at a higher age in women compared with men (mean age 79.5 years vs. 74.7 years, __P__ = 0.009). The age‐adjusted relative risk of HS during OA treatment was 10.9 (CI 6.7–17.6) for men and 9.3 (CI 5.7–15.0) for women, as compared with the untreated general population. Number needed to harm (NNH) (person‐years) was 103 for men and 188 for women. Adjuste

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Author

A. Själander; G. Engström; E. Berntorp; P. Svensson

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0954-6820)

Published

2003

Language

EN

Field

Medicine (Health Sciences)