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Nanoparticles as Respiratory Drug Carriers by sjtudizhang is a document available to read on EtoBox.
This study explores the potential of nanoparticles (NPs) as respiratory drug carriers by examining their interactions with pulmonary surfactant (PS) using coarse-grained molecular dynamics simulations. The results indicate that hydrophilic NPs can easily penetrate the DPPC monolayer with minimal disruption, while hydrophobic NPs cause significant structural disruptions, particularly during compression. The findings provide insights for the molecular design of NPs to enhance their effectiveness in pulmonary
- Author
- sjtudizhang
- Language
- EN