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Can I read Functional Evidence of Low-pressure Cardiopulmonary Baroreceptor Reinnervation 1 Year After Heart Transplantation on EtoBox?

Functional Evidence of Low-pressure Cardiopulmonary Baroreceptor Reinnervation 1 Year After Heart Transplantation by Vegard Bruun Bratholm Wyller; Sissel Nygaard; Anders Haugom Christensen; Katrine Rolid; Kari Nytrøen; Lars Gullestad; Arnt Fiane; Erik Thaulow; Gaute Døhlen; J. Philip Saul is a Medicine article available to read on EtoBox.

What is Functional Evidence of Low-pressure Cardiopulmonary Baroreceptor Reinnervation 1 Year After Heart Transplantation about?

## Purpose: Heart transplantation (htx) implies denervation of afferent neural connections. reinnervation of low-pressure cardiopulmonary baroreceptors might impact the development and treatment of hypertension, but little is known of its occurrence. the present prospective study investigated possible afferent reinnervation of low-pressure cardiopulmonary baroreceptors during the first year after heart transplantation. ## Methods: A total of 50 heart transplant recipients (htxrs) were included and were evaluated 7-12 weeks after transplant surgery, with follow-up 6 and 12 months later. in addition, a reference group of 50 healthy control subjects was examined once. continuous, non-invasive recordings of cardiovascular variables were carried out at supine rest, during 15 min of 20° head-up tilt, during valsalva maneuver and during 1 min of 30% maximal voluntary handgrip. in addition, routine clinical data including invasive measurements were used in the analyses. ## Results: During the first year after htx, the heart rate (hr) response to 20° head-up tilt partly normalized, a negative relationship between resting mean right atrial pressure and hr tilt response developed, low-frequen

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Author
Vegard Bruun Bratholm Wyller; Sissel Nygaard; Anders Haugom Christensen; Katrine Rolid; Kari Nytrøen; Lars Gullestad; Arnt Fiane; Erik Thaulow; Gaute Døhlen; J. Philip Saul
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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