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Pulsed Field Ablation Using Focal Contact Force-sensing Catheters for Treatment of Atrial Fibrillation: Acute and 90-Day Invasive Remapping Results by Ante Anić; Thomas Phlips; Toni Brešković; Pieter Koopman; Steven Girouard; Vikramaditya Mediratta; Zrinka Jurišić; Ivan Sikirić; Lucija Lisica; Johan Vijgen is a Medicine article available to read on EtoBox.
What is Pulsed Field Ablation Using Focal Contact Force-sensing Catheters for Treatment of Atrial Fibrillation: Acute and 90-Day Invasive Remapping Results about?
## Abstract ## Aims Pulsed field ablation (PFA) has emerged as a promising alternative to thermal ablation for treatment of atrial fibrillation (AF). We report performance and safety using the CENTAURITM System (Galvanize Therapeutics) with three commercial, focal ablation catheters. ## Methods and results ECLIPSE AF (NCT04523545) was a prospective, single-arm, multi-centre study evaluating safety and acute and chronic pulmonary vein isolation (PVI) durability using the CENTAURI System in conjunction with the TactiCath SE, StablePoint, and ThermoCool ST ablation catheters. Patients with paroxysmal or persistent AF were treated at two centres. Patients were analysed in five cohorts based upon ablation settings, catheter, and mapping system. Pulsed field ablation was performed in 82 patients (74% male, 42 paroxysmal AF). Pulmonary vein isolation was achieved in 100% of pulmonary veins (322/322) with first-pass isolation in 92.2% (297/322). There were four serious adverse events of interest (three vascular access complications and one lacunar stroke). Eighty patients (98%) underwent invasive remapping. Pulsed field ablation development Cohorts 1 and 2 showed a per-patient isolation ra
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- Author
- Ante Anić; Thomas Phlips; Toni Brešković; Pieter Koopman; Steven Girouard; Vikramaditya Mediratta; Zrinka Jurišić; Ivan Sikirić; Lucija Lisica; Johan Vijgen
- Publisher
- Oxford University Press (OUP)
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)