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Upconversion Nanomaterials and Delivery Systems for Smart Photonic Medicines and Healthcare Devices by Gibum Lee; Hye Eun Choi; Sang Hoon Hong; Minji Choi; Dong-Wook Han; Junmin Lee; Ki Su Kim; Sei Kwang Hahn is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

In the past decade, upconversion (UC) nanomaterials have been extensively investigated for the applications to photomedicines with their unique features including biocompatibility, near-infrared (NIR) to visible conversion, photostability, controllable emission bands, and facile multi-functionality. These characteristics of UC nanomaterials enable versatile light delivery for deep tissue biophotonic applications. Among various stimuli-responsive delivery systems, the light-responsive delivery process has been greatly advantageous to develop spatiotemporally controllable on-demand "smart" photonic medicines. UC nanomaterials are classified largely to two groups depending on the photon UC pathway and compositions: inorganic lanthanide-doped UC nanoparticles and organic triplet-triplet annihilation UC (TTA-UC) nanomaterials. Here, we review the current-state-of-art inorganic and organic UC nanomaterials for photo-medicinal applications including photothermal therapy (PTT), photodynamic therapy (PDT), photo-triggered chemo and gene therapy, multimodal immunotherapy, NIR mediated neuromodulations, and photochemical tissue bonding (PTB). We also discuss the future research direction of t

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Gibum Lee; Hye Eun Choi; Sang Hoon Hong; Minji Choi; Dong-Wook Han; Junmin Lee; Ki Su Kim; Sei Kwang Hahn
Publisher
Elsevier BV
Published
2022
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)