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Can I read Tissue Zinc Concentration in Prostate Cancer: Relationship with Prostate Specific Antigen and Gleason Score in a Cohort of Nigerian Men on EtoBox?
Tissue Zinc Concentration in Prostate Cancer: Relationship with Prostate Specific Antigen and Gleason Score in a Cohort of Nigerian Men by Martin Igbokwe; Ayo Salako; Tajudeen Badmus; Eusebius Obiajunwa; Olalekan Olasehinde; Chiamaka Igbokwe; Rotimi David is a Medicine article available to read on EtoBox.
What is Tissue Zinc Concentration in Prostate Cancer: Relationship with Prostate Specific Antigen and Gleason Score in a Cohort of Nigerian Men about?
Introduction: Prostate cancer (PCa) is the commonest maliganacy among men of African descent. The possible role of trace elements like Zinc in its aetiogenesis and disease severity remains controversial. This paper aims to identify the relationship between tissue zinc concentration and the occurrence of prostate cancer. And to identify the relationship between the tissue zinc concentration and the disease severity (using the prostate specific antigen (PSA) and Gleason scores (GS)).Methodology: A cross-sectional study of 41 consecutive consenting men with histologically confirmed PCa and 41 age-matched controls. Toe-nail clippings were obtained from both groups and assayed for zinc using the Particle induced X-ray emission (PIXE) technique. Zinc concentrations were compared between cases and controls. A correlation analysis was performed to determine relationship between Zinc concentration and disease severity (PSA and GS). Results: Forty one men each were recruited in the Prostate cancer and control groups for this study. PCa group had a mean age of 72.83 ± 7.06 years while the control group was 70.73 ±6.40 years. There was statistically significant higher toe-nail Zn concentration
Who reads Tissue Zinc Concentration in Prostate Cancer: Relationship with Prostate Specific Antigen and Gleason Score in a Cohort of Nigerian Men?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Martin Igbokwe; Ayo Salako; Tajudeen Badmus; Eusebius Obiajunwa; Olalekan Olasehinde; Chiamaka Igbokwe; Rotimi David
- Publisher
- EpiSmart Science Vector Ltd
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)