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Medical Management of Cutaneous Sulfur Mustard Injuries by John S. Graham; Robert S. Stevenson; Larry W. Mitcheltree; Tracey A. Hamilton; Robin R. Deckert; Robyn B. Lee; Ann M. Schiavetta is a Environmental Science article available to read on EtoBox.

What is Medical Management of Cutaneous Sulfur Mustard Injuries about?

Background: Sulfur mustard (2,2 -dichlorodiethyl sulfide; HD) is a potent vesicating chemical warfare agent that poses a continuing threat to both military and civilian populations. Significant cutaneous HD injuries can take several months to heal, necessitate lengthy hospitalizations, and result in long-term complications. There are currently no standardized or optimized methods of casualty management. New strategies are needed to provide for optimal and rapid wound healing. Objective: The primary aim of this research was to develop improved clinical strategies (treatment guidelines) for optimal treatment of superficial dermal (second degree) cutaneous HD injuries, with the goal of returning damaged skin to optimal appearance and normal function in the shortest period of time. Methods: Superficial dermal HD injuries were created on the ventral abdominal surface of weanling pigs. At 48 h post-exposure, lesions were laser debrided and a treatment adjunct applied. Cultured epithelial allografts and 11 commercial off-the-shelf (COTS) products were examined for their efficacy in improving wound healing of these injuries. Clinical evaluations and a variety of non-invasive bioengineering

Who reads Medical Management of Cutaneous Sulfur Mustard Injuries?

Author

John S. Graham; Robert S. Stevenson; Larry W. Mitcheltree; Tracey A. Hamilton; Robin R. Deckert; Robyn B. Lee; Ann M. Schiavetta

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0300-483X)

Published

2009

Language

EN

Field

Environmental Science (Life Sciences)