Opening book details…
Can I read A Simple Method to Heparinize Biological Materials on EtoBox?
A Simple Method to Heparinize Biological Materials by Yasuharu Noishiki; Teruo Miyata is a Medicine article available to read on EtoBox.
What is A Simple Method to Heparinize Biological Materials about?
A new method was developed inducing antithrombogenicity to biologic materials. A basic protein, protamine, was used to increase heparin binding to collagenous materials. Protamine sulfate solution was poured into a collagen-rich material (porcine ureter). The protamine adsorbed to the collagen was then cross-linked to the material by glutaraldehyde. The collagen-protamine complex was then interacted with a heparin solution to ionically bind heparin to the material. The amount and the distribution of the bound heparin can be controlled by changing the protamine fixation to the material. A heparinized porcine ureter as a vascular substitute showed excellent antithrombogenicity in experimental animal studies. This method is expected to be used as method for developing antithrombogenic artificial organs, and as a method for the development of antiadhesive membranes.
Who reads A Simple Method to Heparinize Biological Materials?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Yasuharu Noishiki; Teruo Miyata
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Heterocorporation; Wiley (ISSN 0021-9304)
- Published
- 1986
- Language
- EN
- Field
- Medicine (Health Sciences)