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Can I read Localized Hyperthermic Treatment of Experimental Bone Tumors with Ferromagnetic Ceramics on EtoBox?

Localized Hyperthermic Treatment of Experimental Bone Tumors with Ferromagnetic Ceramics by Dr. Minoru Ikenaga; Kouichiro Ohura; Takao Yamamuro; Yoshihiko Kotoura; Masanori Oka; Tadashi Kokubo is a Medicine article available to read on EtoBox.

What is Localized Hyperthermic Treatment of Experimental Bone Tumors with Ferromagnetic Ceramics about?

## Abstract Localized hyperthermic treatment was carried out with use of a metastatic bone tumor model in rabbits. The experimental bone tumor was created by transplantation of pieces of tumor line VX2 into the medullary canal of rabbit tibiae. Two weeks after the transplantation, a ferromagnetic ceramic pin was inserted in the medullary canal. Then, hyperthermia (HT) of the tumor was accomplished with use of an alternating magnetic field for 50 min. All the rabbits were killed 5 weeks after tumor transplantation, and the therapeutic effect was evaluated histologically and roentgenographically. Almost all the tumor cells within the bone marrow were killed by the procedure. The area of the tumor necrosis in the HT group was significnatly larger than in the control group. The pathological fracture rate and displacement rate were reduced significantly by this treatment (38.5 and 0%) compared with the controls (92.3 and 92.3%). Therefore, HT with the use of ferromagnetic ceramics was effective for local control of malignant bone tumors and seems to be a promising new method of treatment.

Who reads Localized Hyperthermic Treatment of Experimental Bone Tumors with Ferromagnetic Ceramics?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Dr. Minoru Ikenaga; Kouichiro Ohura; Takao Yamamuro; Yoshihiko Kotoura; Masanori Oka; Tadashi Kokubo
Publisher
Elsevier Science; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 0736-0266)
Published
1993
Language
EN
Field
Medicine (Health Sciences)

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