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The Role of Genetics in Breast and Reproductive Cancers (Cancer Genetics) by Robin L. Bennett (auth.), Piri Welcsh (eds.) is a nonfiction available to read on EtoBox.

What is The Role of Genetics in Breast and Reproductive Cancers (Cancer Genetics) about?

Of all factors contributing to breast cancer, family history of disease is the most powerful. Currently, our understanding of genetic predisposition to breast cancer includes three classes of genes as defined by their associated risks. BRCA1 and BRCA2 are high-penetrance breast cancer predisposition genes. Since the cloning of BRCA1 and BRCA2, inherited mutations in an additional 8 genes, all of which are functionally related to BRCA1 and/or BRCA2, have been shown to variously confer a low-intermediate increased breast cancer risk. Furthermore, recent genome-wide association studies have uncovered eight common variants associated with low-penetrance breast cancer predisposition. Despite these discoveries, most of the familial risk of breast cancer remains unexplained. The Role of Genetics in Breast and Reproductive Cancers is divided into three parts: Recognition of Hereditary Breast and Reproductive Cancer Syndromes, Genetic etiology of breast and reproductive cancers, and Genes and the environment. In the first section, we discuss how genetic counselors and clinicians acknowledge hereditary breast and reproductive cancer syndromes, with an emphasis on the challenges and responsib

Who reads The Role of Genetics in Breast and Reproductive Cancers (Cancer Genetics)?

Author

Robin L. Bennett (auth.), Piri Welcsh (eds.)

Publisher

Springer-Verlag New York

Published

2010

Language

EN

ISBN

9781441904768

Category

nonfiction

Subjects

Medical, Medicine