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Can I read Transmission electron microscopy as a tool to image bioinorganic nanohybrids: The case of phage-gold nanocomposites on EtoBox?
Transmission electron microscopy as a tool to image bioinorganic nanohybrids: The case of phage-gold nanocomposites by Binrui Cao; Hong Xu; Chuanbin Mao is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Transmission electron microscopy as a tool to image bioinorganic nanohybrids: The case of phage-gold nanocomposites about?
## Abstract In recent years, bioinorganic nanohybrids composed of biological macromolecules and functional inorganic nanomaterials have revealed many unique properties that show promise for the future. Transmission electron microscopy (TEM) is a popular and relatively simple tool that can offer a direct visualization of the nanomaterials with high resolutions. When TEM is applied to visualize bioinorganic nanohybrids, a treatment of negative staining is necessary due to the presence of biological molecules in the nanohybrids except for those with densely packed inorganic materials. However, the conventional negative‐staining procedure for regular biological samples cannot be directly applied to such bioinorganic nanohybrids. To image a specific bioinorganic nanohybrid, negative‐staining factors such as negative stain type, working pH, staining time, and drying method, should be identified. Currently, no detailed studies have been done to investigate how to adjust negative‐staining factors based on specific bioinorganic nanohybrids. In this study, bacteriophage‐gold nanoparticle hybrids were chosen as a model to systematically study the effects of each factor on the negative stainin
Who reads Transmission electron microscopy as a tool to image bioinorganic nanohybrids: The case of phage-gold nanocomposites?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Binrui Cao; Hong Xu; Chuanbin Mao
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1059-910X)
- Published
- 2011
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)