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Can I read Myotonia in Colchicine Myoneuropathy on EtoBox?
Myotonia in Colchicine Myoneuropathy by Seward B. Rutkove; Umberto De Girolami; David C. Preston; Roy Freeman; Rachel A. Nardin; Gunnar K. Gouras; Donald R. Johns; Elizabeth M. Raynor is a Medicine article available to read on EtoBox.
What is Myotonia in Colchicine Myoneuropathy about?
## ~~ Colchicine may induce a myoneuropathy in patients with renal insufficiency. To date, myotonia has not been described in this disorder. We recently studied 4 patients treated with routine doses of colchicine who, in the setting of renal insufficiency, developed a severe myoneuropathy characterized by prominent myotonic discharges on electromyography. In addition, 1 of the 4 patients had profound clinical myotonia. In the 3 patients in whom biopsies were performed, marked myopathic change with intracytoplasmic vacuolization was identified. All 4 patients improved rapidly with discontinuation of the medication. The patient in whom electrophysiologic studies were repeated had a complete resolution of the myotonic discharges. Colchicine myoneuropathy can present with prominent clinical and electrophysiologic myotonia that resolves completely with discontinuation of the medication.
Who reads Myotonia in Colchicine Myoneuropathy?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Seward B. Rutkove; Umberto De Girolami; David C. Preston; Roy Freeman; Rachel A. Nardin; Gunnar K. Gouras; Donald R. Johns; Elizabeth M. Raynor
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0148-639X)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)